Researchers from The Ohio State University, have developed an innovative new device that can develop new cells within a patient’s own body, simply by acting on the skin. The technology could open up a host of new treatment options in medicine.
The technology is known as Tissue Nanotransfection (THT). It involves using a nanotechnology-based chip and placing it on the skin of a patient. It can convert an adult cell from one type to another, simply by “zapping” the device with a small electrical charge. The procedure is non-invasive. The findings are published in the journal Nature Nanotechnology.
"By using our novel nanochip technology, injured or compromised organs can be replaced,” said study co-author Dr Chandan Sen in a statement. “We have shown that skin is a fertile land where we can grow the elements of any organ that is declining.”
The device has not yet been tested in humans, but it has proved successful with mice. In a mouse that had leg injuries, within one week the chip caused active blood vessels to re-appear, and by the second week the leg was saved. It also helped brain-injured mice recover from a stroke.
"The chip carries a specific genetic code in the form of DNA or RNA, which, when applied to cells, changes them from their previous structure and function to the structure and functions needed to repair the injury,"
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